The people you are talking to have apparently never seen this research. Maybe you can help them out and provide links? It's faster to do that than to engage in some form of audience-persuasion, as well as more effective.
They are idealists but also like cryptocurrency and decentralization. I recognize that's pretty rare since the late 2010's reputation of various coins and their environmental impact but IA is heavily associated with (and received much money from) FileCoin:
(and I am not saying it's bad, or indeed good, just that the usual expectations of being pro- or anti- cryptocurrency or AI don't easily map to things like the Archive)
No, the evidence is that there is no significant difference in satiety. HFCS is 55% fructose / 45% glucose, while sucrose is 50% fructose / 50% glucose.
Not saying Sugar itself is much better, however, yes, there is research indicating that the two are metabolized differently, so that difference in composition should be considered.
I am entirely unconvinced that a 5% difference in fructose vs. glucose is a meaningful difference.
They carry the same health risks if eaten in the same amounts. The only thing that corn syrup could be blamed for here is being too cheap so it shows up in greater quantity and in more products than cane sugar might otherwise.
HFCS is just one of those fashionable things to be "concerned" about so we can all miss the forest through the trees.
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