> I would expect the proportion of people > 50 that perform resistance based weight training to be small. Adding a drug that diminishes your muscle mass when you can least afford to lose it sounds like it could be terrible for that aging population.
Then prescribe weight training in addition to it. This isn't rocket science. Older folks should be doing exercise to offset the potential loss in muscle and bone mass anyway. It works. We've proven it works. We've proven it improves health outcomes and quality of life long-term going into old age. This isn't just something that should be waved away with "ah, well, we've proven people lose muscle mass, nothing we can do about it".
Then prescribe weight training in addition to it. This isn't rocket science. Older folks should be doing exercise to offset the potential loss in muscle and bone mass anyway. It works. We've proven it works. We've proven it improves health outcomes and quality of life long-term going into old age. This isn't just something that should be waved away with "ah, well, we've proven people lose muscle mass, nothing we can do about it".